node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mpe_A0629 | Mpe_A2082 | Mpe_A0629 | Mpe_A2082 | Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family. | N-acetylglucosamine kinase. | 0.946 |
Mpe_A0629 | Mpe_A2729 | Mpe_A0629 | Mpe_A2729 | Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family. | Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.918 |
Mpe_A0629 | pfp | Mpe_A0629 | Mpe_A2776 | Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family. | Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.925 |
Mpe_A0629 | pgi | Mpe_A0629 | Mpe_A3094 | Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.950 |
Mpe_A2082 | Mpe_A0629 | Mpe_A2082 | Mpe_A0629 | N-acetylglucosamine kinase. | Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.946 |
Mpe_A2082 | Mpe_A2729 | Mpe_A2082 | Mpe_A2729 | N-acetylglucosamine kinase. | Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.946 |
Mpe_A2082 | pfp | Mpe_A2082 | Mpe_A2776 | N-acetylglucosamine kinase. | Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.937 |
Mpe_A2082 | pgi | Mpe_A2082 | Mpe_A3094 | N-acetylglucosamine kinase. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.939 |
Mpe_A2082 | pykF | Mpe_A2082 | Mpe_A0290 | N-acetylglucosamine kinase. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.406 |
Mpe_A2729 | Mpe_A0629 | Mpe_A2729 | Mpe_A0629 | Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family. | Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.918 |
Mpe_A2729 | Mpe_A2082 | Mpe_A2729 | Mpe_A2082 | Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family. | N-acetylglucosamine kinase. | 0.946 |
Mpe_A2729 | pfp | Mpe_A2729 | Mpe_A2776 | Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family. | Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.925 |
Mpe_A2729 | pgi | Mpe_A2729 | Mpe_A3094 | Mannose-1-phosphate guanylyltransferase (GDP); Belongs to the mannose-6-phosphate isomerase type 2 family. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.950 |
cbbT | eno | Mpe_A2790 | Mpe_A2847 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.926 |
cbbT | pfp | Mpe_A2790 | Mpe_A2776 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.922 |
cbbT | pgi | Mpe_A2790 | Mpe_A3094 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.966 |
cbbT | pykF | Mpe_A2790 | Mpe_A0290 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.908 |
cbbT | tal | Mpe_A2790 | Mpe_A3095 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. | 0.986 |
cbbT | tktA | Mpe_A2790 | Mpe_A0259 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Transketolase; Belongs to the transketolase family. | 0.902 |
cbbT | tpiA | Mpe_A2790 | Mpe_A1401 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.950 |