node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mpe_A1521 | Mpe_A3255 | Mpe_A1521 | Mpe_A3255 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.917 |
Mpe_A1521 | eno | Mpe_A1521 | Mpe_A2847 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.934 |
Mpe_A1521 | pckG | Mpe_A1521 | Mpe_A3705 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.921 |
Mpe_A1521 | ppc | Mpe_A1521 | Mpe_A3003 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. | 0.917 |
Mpe_A1521 | pykF | Mpe_A1521 | Mpe_A0290 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.930 |
Mpe_A3255 | Mpe_A1521 | Mpe_A3255 | Mpe_A1521 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.917 |
Mpe_A3255 | cbbK | Mpe_A3255 | Mpe_A2792 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.836 |
Mpe_A3255 | eno | Mpe_A3255 | Mpe_A2847 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.920 |
Mpe_A3255 | mdh | Mpe_A3255 | Mpe_A2172 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.917 |
Mpe_A3255 | pckG | Mpe_A3255 | Mpe_A3705 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.917 |
Mpe_A3255 | pgk | Mpe_A3255 | Mpe_A0289 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.836 |
Mpe_A3255 | ppc | Mpe_A3255 | Mpe_A3003 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. | 0.921 |
Mpe_A3255 | pykF | Mpe_A3255 | Mpe_A0290 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.917 |
Mpe_A3255 | sucC-2 | Mpe_A3255 | Mpe_A3257 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.933 |
Mpe_A3255 | sucD-2 | Mpe_A3255 | Mpe_A3256 | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.958 |
cbbK | Mpe_A3255 | Mpe_A2792 | Mpe_A3255 | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.836 |
cbbK | eno | Mpe_A2792 | Mpe_A2847 | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.955 |
cbbK | mdh | Mpe_A2792 | Mpe_A2172 | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.477 |
cbbK | pgk | Mpe_A2792 | Mpe_A0289 | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.902 |
cbbK | ppc | Mpe_A2792 | Mpe_A3003 | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. | 0.836 |