node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mpe_A0028 | Mpe_A0166 | Mpe_A0028 | Mpe_A0166 | O-acetylhomoserine aminocarboxypropyltransferase. | Methionine synthase (B12-dependent). | 0.932 |
Mpe_A0028 | Mpe_A0168 | Mpe_A0028 | Mpe_A0168 | O-acetylhomoserine aminocarboxypropyltransferase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.932 |
Mpe_A0028 | Mpe_A0450 | Mpe_A0028 | Mpe_A0450 | O-acetylhomoserine aminocarboxypropyltransferase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.846 |
Mpe_A0028 | Mpe_A1541 | Mpe_A0028 | Mpe_A1541 | O-acetylhomoserine aminocarboxypropyltransferase. | Homoserine dehydrogenase. | 0.873 |
Mpe_A0028 | Mpe_A1615 | Mpe_A0028 | Mpe_A1615 | O-acetylhomoserine aminocarboxypropyltransferase. | Cystathionine beta-lyase. | 0.944 |
Mpe_A0028 | Mpe_A3770 | Mpe_A0028 | Mpe_A3770 | O-acetylhomoserine aminocarboxypropyltransferase. | L-threonine ammonia-lyase. | 0.834 |
Mpe_A0028 | ahcY | Mpe_A0028 | Mpe_A3286 | O-acetylhomoserine aminocarboxypropyltransferase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.921 |
Mpe_A0028 | ilvA | Mpe_A0028 | Mpe_A3125 | O-acetylhomoserine aminocarboxypropyltransferase. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.811 |
Mpe_A0028 | metZ | Mpe_A0028 | Mpe_A2150 | O-acetylhomoserine aminocarboxypropyltransferase. | Cystathionine gamma-synthase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.935 |
Mpe_A0166 | Mpe_A0028 | Mpe_A0166 | Mpe_A0028 | Methionine synthase (B12-dependent). | O-acetylhomoserine aminocarboxypropyltransferase. | 0.932 |
Mpe_A0166 | Mpe_A0168 | Mpe_A0166 | Mpe_A0168 | Methionine synthase (B12-dependent). | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.999 |
Mpe_A0166 | Mpe_A0450 | Mpe_A0166 | Mpe_A0450 | Methionine synthase (B12-dependent). | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.842 |
Mpe_A0166 | Mpe_A1541 | Mpe_A0166 | Mpe_A1541 | Methionine synthase (B12-dependent). | Homoserine dehydrogenase. | 0.876 |
Mpe_A0166 | Mpe_A1615 | Mpe_A0166 | Mpe_A1615 | Methionine synthase (B12-dependent). | Cystathionine beta-lyase. | 0.950 |
Mpe_A0166 | Mpe_A3770 | Mpe_A0166 | Mpe_A3770 | Methionine synthase (B12-dependent). | L-threonine ammonia-lyase. | 0.839 |
Mpe_A0166 | ahcY | Mpe_A0166 | Mpe_A3286 | Methionine synthase (B12-dependent). | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.940 |
Mpe_A0166 | ilvA | Mpe_A0166 | Mpe_A3125 | Methionine synthase (B12-dependent). | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.839 |
Mpe_A0166 | metZ | Mpe_A0166 | Mpe_A2150 | Methionine synthase (B12-dependent). | Cystathionine gamma-synthase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.950 |
Mpe_A0168 | Mpe_A0028 | Mpe_A0168 | Mpe_A0028 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine aminocarboxypropyltransferase. | 0.932 |
Mpe_A0168 | Mpe_A0166 | Mpe_A0168 | Mpe_A0166 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine synthase (B12-dependent). | 0.999 |