node1 | node2 | node1 annotation | node2 annotation | score |
A0A2T6ZEE8 | A0A2T6ZKR1 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | ATP phosphoribosyltransferase-domain-containing protein. | 0.994 |
A0A2T6ZEE8 | A0A2T6ZMF3 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Histidine biosynthesis trifunctional protein. | 0.997 |
A0A2T6ZEE8 | A0A2T6ZRP5 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.997 |
A0A2T6ZEE8 | A0A2T7A6F8 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.996 |
A0A2T6ZEE8 | A0A2T7A7V0 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | Pyridoxal phosphate-dependent transferase. | 0.994 |
A0A2T6ZGU7 | A0A2T6ZKR1 | AA_TRNA_LIGASE_II domain-containing protein. | ATP phosphoribosyltransferase-domain-containing protein. | 0.870 |
A0A2T6ZGU7 | A0A2T6ZM82 | AA_TRNA_LIGASE_II domain-containing protein. | Kinase-like domain-containing protein. | 0.539 |
A0A2T6ZGU7 | A0A2T6ZMF3 | AA_TRNA_LIGASE_II domain-containing protein. | Histidine biosynthesis trifunctional protein. | 0.916 |
A0A2T6ZGU7 | A0A2T6ZU64 | AA_TRNA_LIGASE_II domain-containing protein. | Protein kinase domain-containing protein. | 0.539 |
A0A2T6ZGU7 | A0A2T6ZUP1 | AA_TRNA_LIGASE_II domain-containing protein. | Kinase-like domain-containing protein. | 0.539 |
A0A2T6ZGU7 | A0A2T7A4Y8 | AA_TRNA_LIGASE_II domain-containing protein. | tRNA-synt_His domain-containing protein. | 0.884 |
A0A2T6ZKR1 | A0A2T6ZEE8 | ATP phosphoribosyltransferase-domain-containing protein. | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. | 0.994 |
A0A2T6ZKR1 | A0A2T6ZGU7 | ATP phosphoribosyltransferase-domain-containing protein. | AA_TRNA_LIGASE_II domain-containing protein. | 0.870 |
A0A2T6ZKR1 | A0A2T6ZM82 | ATP phosphoribosyltransferase-domain-containing protein. | Kinase-like domain-containing protein. | 0.870 |
A0A2T6ZKR1 | A0A2T6ZMF3 | ATP phosphoribosyltransferase-domain-containing protein. | Histidine biosynthesis trifunctional protein. | 0.998 |
A0A2T6ZKR1 | A0A2T6ZRP5 | ATP phosphoribosyltransferase-domain-containing protein. | Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.980 |
A0A2T6ZKR1 | A0A2T6ZU64 | ATP phosphoribosyltransferase-domain-containing protein. | Protein kinase domain-containing protein. | 0.870 |
A0A2T6ZKR1 | A0A2T6ZUP1 | ATP phosphoribosyltransferase-domain-containing protein. | Kinase-like domain-containing protein. | 0.870 |
A0A2T6ZKR1 | A0A2T7A4Y8 | ATP phosphoribosyltransferase-domain-containing protein. | tRNA-synt_His domain-containing protein. | 0.870 |
A0A2T6ZKR1 | A0A2T7A6F8 | ATP phosphoribosyltransferase-domain-containing protein. | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. | 0.994 |