STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. (311 aa)    
Predicted Functional Partners:
Ssed_2358
Hydrolyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.994
Ssed_2819
KEGG: slo:Shew_1650 citrate synthase I; Belongs to the citrate synthase family.
  
 0.994
fumC
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.975
Ssed_2112
KEGG: slo:Shew_1821 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family.
  
 0.975
Ssed_2273
KEGG: ppr:PBPRA1988 putative pyruvate oxidoreductase.
  
  
 0.969
Ssed_1321
KEGG: slo:Shew_1220 oxaloacetate decarboxylase alpha subunit.
    
 0.946
Ssed_0538
KEGG: slo:Shew_0383 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)).
  
 0.944
maeA
KEGG: slo:Shew_2962 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); Belongs to the malic enzymes family.
  
 0.944
Ssed_2301
KEGG: slo:Shew_1951 aspartate transaminase.
   
 0.936
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
  
 
 0.936
Your Current Organism:
Shewanella sediminis
NCBI taxonomy Id: 425104
Other names: S. sediminis HAW-EB3, Shewanella sediminis HAW-EB3, Shewanella sediminis str. HAW-EB3, Shewanella sediminis strain HAW-EB3
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.