STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (426 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.990
hemL
KEGG: slo:Shew_1012 glutamate-1-semialdehyde-2,1-aminomutase.
 
 0.989
Ssed_3645
KEGG: cps:CPS_1338 putative glutamate-1-semialdehyde-2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.986
Ssed_3708
KEGG: cps:CPS_3593 putative glutamate-1-semialdehyde-2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 0.985
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
     
 0.930
Ssed_2088
Uroporphyrinogen-III methylase-like protein; KEGG: dps:DP1734 probable uroporphyrinogen III synthase/methyltransferase (HemD+CobA); Belongs to the precorrin methyltransferase family.
 
  
 0.913
Ssed_4105
KEGG: slo:Shew_3382 porphobilinogen synthase; Belongs to the ALAD family.
 
  
 0.881
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
  
 0.864
Ssed_3797
KEGG: sbl:Sbal_3409 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.780
Ssed_2768
KEGG: sfr:Sfri_1506 uroporphyrin-III C-methyltransferase.
 
  
 0.774
Your Current Organism:
Shewanella sediminis
NCBI taxonomy Id: 425104
Other names: S. sediminis HAW-EB3, Shewanella sediminis HAW-EB3, Shewanella sediminis str. HAW-EB3, Shewanella sediminis strain HAW-EB3
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