node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ssed_0433 | Ssed_1126 | Ssed_0433 | Ssed_1126 | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | 0.905 |
Ssed_0433 | Ssed_2358 | Ssed_0433 | Ssed_2358 | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | Hydrolyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.436 |
Ssed_0433 | Ssed_4160 | Ssed_0433 | Ssed_4160 | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | KEGG: slo:Shew_0294 alanine--glyoxylate transaminase. | 0.905 |
Ssed_0433 | gcvH | Ssed_0433 | Ssed_3674 | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.980 |
Ssed_0433 | gcvP | Ssed_0433 | Ssed_3673 | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | 2-alkenal reductase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.958 |
Ssed_0433 | gcvT | Ssed_0433 | Ssed_3675 | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.960 |
Ssed_0433 | glyA | Ssed_0433 | Ssed_1271 | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.933 |
Ssed_1126 | Ssed_0433 | Ssed_1126 | Ssed_0433 | KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | 0.905 |
Ssed_1126 | Ssed_1247 | Ssed_1126 | Ssed_1247 | KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | KEGG: slo:Shew_1155 threonine aldolase. | 0.423 |
Ssed_1126 | Ssed_4160 | Ssed_1126 | Ssed_4160 | KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | KEGG: slo:Shew_0294 alanine--glyoxylate transaminase. | 0.526 |
Ssed_1126 | gcvH | Ssed_1126 | Ssed_3674 | KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.879 |
Ssed_1126 | gcvP | Ssed_1126 | Ssed_3673 | KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | 2-alkenal reductase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.972 |
Ssed_1126 | gcvT | Ssed_1126 | Ssed_3675 | KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.891 |
Ssed_1126 | glyA | Ssed_1126 | Ssed_1271 | KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.447 |
Ssed_1247 | Ssed_1126 | Ssed_1247 | Ssed_1126 | KEGG: slo:Shew_1155 threonine aldolase. | KEGG: slo:Shew_1032 glutamate synthase (ferredoxin). | 0.423 |
Ssed_1247 | Ssed_4160 | Ssed_1247 | Ssed_4160 | KEGG: slo:Shew_1155 threonine aldolase. | KEGG: slo:Shew_0294 alanine--glyoxylate transaminase. | 0.933 |
Ssed_1247 | gcvP | Ssed_1247 | Ssed_3673 | KEGG: slo:Shew_1155 threonine aldolase. | 2-alkenal reductase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.948 |
Ssed_1247 | glyA | Ssed_1247 | Ssed_1271 | KEGG: slo:Shew_1155 threonine aldolase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.942 |
Ssed_1247 | kbl | Ssed_1247 | Ssed_0101 | KEGG: slo:Shew_1155 threonine aldolase. | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.919 |
Ssed_2358 | Ssed_0433 | Ssed_2358 | Ssed_0433 | Hydrolyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | KEGG: slo:Shew_3429 dihydrolipoamide dehydrogenase. | 0.436 |