STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M446_1338PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rxy:Rxyl_1762 enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (250 aa)    
Predicted Functional Partners:
M446_6079
PFAM: AMP-dependent synthetase and ligase; KEGG: scl:sce8262 non-ribosomal peptide synthetase.
  
 0.883
M446_1337
Coenzyme A transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family.
 
   
 0.835
M446_3478
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: dac:Daci_2758 enoyl-CoA hydratase/isomerase.
 
 
0.785
M446_0768
PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: mex:Mext_1544 3-hydroxybutyryl-CoA dehydrogenase.
 
 0.771
M446_2005
PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: mex:Mext_1544 3-hydroxybutyryl-CoA dehydrogenase.
 
 0.762
M446_3936
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: pae:PA2552 probable acyl-CoA dehydrogenase.
 
 0.744
M446_5280
KEGG: mex:Mext_3469 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.717
M446_0317
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: mex:Mext_1947 beta-ketoacyl synthase.
  
 0.716
M446_1246
KEGG: mex:Mext_3469 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.716
M446_3279
KEGG: mex:Mext_3244 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.711
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
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