STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M446_1732PFAM: ribulose bisphosphate carboxylase large chain; KEGG: acr:Acry_1067 ribulose-bisphosphate carboxylase; Belongs to the RuBisCO large chain family. (423 aa)    
Predicted Functional Partners:
M446_2281
PFAM: phosphoribulokinase/uridine kinase; KEGG: mex:Mext_0980 phosphoribulokinase.
 
 
 0.972
M446_1733
PFAM: type III effector Hrp-dependent outers; KEGG: acr:Acry_1068 type III effector Hrp-dependent outer protein.
 
   
 0.955
gph
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
    
 0.929
M446_5852
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mex:Mext_2049 HAD-superfamily hydrolase, subfamily IA, variant 1.
    
 0.929
pgk
PFAM: phosphoglycerate kinase; KEGG: mex:Mext_2368 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
    
 0.928
M446_6369
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mex:Mext_0280 HAD-superfamily hydrolase, subfamily IA, variant 1.
 
  
 0.927
M446_1731
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bpt:Bpet4363 putative short chain dehydrogenase.
       0.773
M446_0468
PFAM: transferase hexapeptide repeat containing protein; KEGG: smd:Smed_1693 transferase hexapeptide repeat containing protein.
    
 
 0.741
M446_1749
KEGG: mex:Mext_1506 carbonic anhydrase/acetyltransferase isoleucine patch superfamily-like protein.
    
 
 0.741
M446_4366
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
  
 0.721
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
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