STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M446_3819TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: smd:Smed_0883 type I secretion membrane fusion protein, HlyD family. (514 aa)    
Predicted Functional Partners:
M446_3820
KEGG: smd:Smed_0884 type I secretion system ATPase; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter transmembrane region; ABC transporter related; peptidase C39 bacteriocin processing; SMART: AAA ATPase.
 
 
 0.976
M446_6669
TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: bra:BRADO6925 putative HlyD family secretion protein.
  
  
 
0.919
M446_3818
PFAM: glycosyl transferase group 1; KEGG: pol:Bpro_4925 glycosyl transferase, group 1.
 
   
 0.815
M446_3382
KEGG: mex:Mext_2739 type I secretion system ATPase; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase.
  
 0.777
M446_1274
KEGG: mex:Mext_1161 type I secretion system ATPase; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; SMART: AAA ATPase.
 
  
 0.774
M446_2512
KEGG: mex:Mext_2739 type I secretion system ATPase; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; SMART: AAA ATPase.
  
 0.774
M446_3317
KEGG: mex:Mext_2739 type I secretion system ATPase; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase.
 
  
 0.770
M446_6263
PFAM: Hemolysin-type calcium-binding region; KEGG: mex:Mext_0131 hemolysin-type calcium-binding region.
 
  
 0.768
macB
ABC transporter related; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.761
M446_3007
PFAM: Hemolysin-type calcium-binding region; KEGG: bja:bll7673 hypothetical protein.
 
  
 0.759
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.