STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mchMethenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family. (324 aa)    
Predicted Functional Partners:
M446_5778
PFAM: Methylene-tetrahydromethanopterin dehydrogenase; KEGG: mex:Mext_1829 methylene-tetrahydromethanopterin dehydrogenase.
 
  
 0.990
ffsA
Formylmethanofuran--tetrahydromethanopterin N-formyltransferase; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family.
 
 
 0.988
M446_6554
Methylenetetrahydrofolate dehydrogenase (NADP(+)); PFAM: Shikimate/quinate 5-dehydrogenase; Methylene-tetrahydromethanopterin dehydrogenase; KEGG: mex:Mext_1797 methylenetetrahydrofolate dehydrogenase (NADP(+)).
 
  
 0.983
M446_5779
PFAM: protein of unknown function DUF201; KEGG: mex:Mext_1830 protein of unknown function DUF201.
 
     0.952
M446_5783
TIGRFAM: formaldehyde-activating enzyme; PFAM: Formaldehyde-activating enzyme (Fae); KEGG: mex:Mext_1834 formaldehyde-activating enzyme.
 
   
 0.895
M446_5782
PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: mex:Mext_1833 triphosphoribosyl-dephospho-CoA protein.
 
     0.885
M446_5781
TIGRFAM: alpha-L-glutamate ligase, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: mex:Mext_1832 alpha-L-glutamate ligase, RimK family; Belongs to the RimK family.
 
     0.877
M446_5775
TIGRFAM: formylmethanofuran dehydrogenase subunit A; PFAM: Amidohydrolase 3; KEGG: mex:Mext_1826 formylmethanofuran dehydrogenase subunit A.
 
   
 0.875
M446_5776
KEGG: mex:Mext_1827 tungsten-containing formylmethanofuran dehydrogenase, subunit B.
 
   
 0.865
M446_4369
TIGRFAM: formaldehyde-activating enzyme; PFAM: Formaldehyde-activating enzyme (Fae); KEGG: mex:Mext_1450 formaldehyde-activating enzyme.
 
   
 0.853
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
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