node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
M446_2679 | M446_6705 | M446_2679 | M446_6705 | KEGG: rru:Rru_A1988 GCN5-related N-acetyltransferase; TIGRFAM: GNAT-family acetyltransferase TIGR03103; PFAM: GCN5-related N-acetyltransferase; RimK domain protein ATP-grasp. | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | 0.550 |
M446_2679 | ftsQ | M446_2679 | M446_6699 | KEGG: rru:Rru_A1988 GCN5-related N-acetyltransferase; TIGRFAM: GNAT-family acetyltransferase TIGR03103; PFAM: GCN5-related N-acetyltransferase; RimK domain protein ATP-grasp. | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | 0.865 |
M446_2679 | ftsZ | M446_2679 | M446_6697 | KEGG: rru:Rru_A1988 GCN5-related N-acetyltransferase; TIGRFAM: GNAT-family acetyltransferase TIGR03103; PFAM: GCN5-related N-acetyltransferase; RimK domain protein ATP-grasp. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.552 |
M446_2679 | mraY | M446_2679 | M446_0258 | KEGG: rru:Rru_A1988 GCN5-related N-acetyltransferase; TIGRFAM: GNAT-family acetyltransferase TIGR03103; PFAM: GCN5-related N-acetyltransferase; RimK domain protein ATP-grasp. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.522 |
M446_2679 | murC | M446_2679 | M446_6703 | KEGG: rru:Rru_A1988 GCN5-related N-acetyltransferase; TIGRFAM: GNAT-family acetyltransferase TIGR03103; PFAM: GCN5-related N-acetyltransferase; RimK domain protein ATP-grasp. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.763 |
M446_2679 | murD | M446_2679 | M446_1685 | KEGG: rru:Rru_A1988 GCN5-related N-acetyltransferase; TIGRFAM: GNAT-family acetyltransferase TIGR03103; PFAM: GCN5-related N-acetyltransferase; RimK domain protein ATP-grasp. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.748 |
M446_2679 | murE | M446_2679 | M446_0260 | KEGG: rru:Rru_A1988 GCN5-related N-acetyltransferase; TIGRFAM: GNAT-family acetyltransferase TIGR03103; PFAM: GCN5-related N-acetyltransferase; RimK domain protein ATP-grasp. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.542 |
M446_2679 | murF | M446_2679 | M446_0259 | KEGG: rru:Rru_A1988 GCN5-related N-acetyltransferase; TIGRFAM: GNAT-family acetyltransferase TIGR03103; PFAM: GCN5-related N-acetyltransferase; RimK domain protein ATP-grasp. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.668 |
M446_2679 | murG | M446_2679 | M446_6704 | KEGG: rru:Rru_A1988 GCN5-related N-acetyltransferase; TIGRFAM: GNAT-family acetyltransferase TIGR03103; PFAM: GCN5-related N-acetyltransferase; RimK domain protein ATP-grasp. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.846 |
M446_6705 | M446_2679 | M446_6705 | M446_2679 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | KEGG: rru:Rru_A1988 GCN5-related N-acetyltransferase; TIGRFAM: GNAT-family acetyltransferase TIGR03103; PFAM: GCN5-related N-acetyltransferase; RimK domain protein ATP-grasp. | 0.550 |
M446_6705 | ddl | M446_6705 | M446_0922 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.928 |
M446_6705 | ftsQ | M446_6705 | M446_6699 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein; Belongs to the FtsQ/DivIB family. FtsQ subfamily. | 0.976 |
M446_6705 | ftsZ | M446_6705 | M446_6697 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.804 |
M446_6705 | mraY | M446_6705 | M446_0258 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.959 |
M446_6705 | murC | M446_6705 | M446_6703 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.985 |
M446_6705 | murD | M446_6705 | M446_1685 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.951 |
M446_6705 | murE | M446_6705 | M446_0260 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.851 |
M446_6705 | murF | M446_6705 | M446_0259 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.929 |
M446_6705 | murG | M446_6705 | M446_6704 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.984 |
ddl | M446_6705 | M446_0922 | M446_6705 | D-alanine--D-alanine ligase; Cell wall formation. | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | 0.928 |