STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M446_6715KEGG: mex:Mext_3923 metal dependent phophohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region. (358 aa)    
Predicted Functional Partners:
M446_4332
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mex:Mext_3983 diguanylate cyclase.
 
 0.867
M446_2827
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mex:Mext_3062 diguanylate cyclase.
   
 0.801
M446_1787
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: aeh:Mlg_1012 diguanylate cyclase.
 
 0.762
M446_2339
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: mex:Mext_2032 diguanylate cyclase; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Diverse 7TM receptor extracellular region 2; Diverse 7TM receptor transmembrane region; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein.
 
 
 0.752
M446_2966
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mex:Mext_1748 diguanylate cyclase.
 
 0.745
M446_0042
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: mex:Mext_3063 diguanylate cyclase.
 
 
 0.741
M446_6542
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sme:SMa2301 putative response regulator.
 
 0.741
M446_4493
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: rpd:RPD_2925 GGDEF domain.
 
 0.740
M446_4577
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: bja:bll5864 hypothetical protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; MHYT domain protein; SMART: PAS domain containing protein.
 
   
 0.732
M446_2203
KEGG: rfr:Rfer_1093 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
   
 0.727
Your Current Organism:
Methylobacterium sp. 446
NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46
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