node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
M446_0710 | lexA | M446_0710 | M446_6716 | PFAM: DNA methylase N-4/N-6 domain protein; KEGG: mex:Mext_3181 DNA methylase N-4/N-6 domain protein; Belongs to the N(4)/N(6)-methyltransferase family. | Transcriptional repressor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.754 |
M446_4497 | M446_6288 | M446_4497 | M446_6288 | KEGG: mex:Mext_4575 hypothetical protein. | KEGG: pin:Ping_0445 membrane protein involved in colicin uptake-like protein. | 0.455 |
M446_4497 | M446_6694 | M446_4497 | M446_6694 | KEGG: mex:Mext_4575 hypothetical protein. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.455 |
M446_4497 | lexA | M446_4497 | M446_6716 | KEGG: mex:Mext_4575 hypothetical protein. | Transcriptional repressor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.793 |
M446_4497 | polA | M446_4497 | M446_0678 | KEGG: mex:Mext_4575 hypothetical protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.805 |
M446_4497 | recA | M446_4497 | M446_0291 | KEGG: mex:Mext_4575 hypothetical protein. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.842 |
M446_6288 | M446_4497 | M446_6288 | M446_4497 | KEGG: pin:Ping_0445 membrane protein involved in colicin uptake-like protein. | KEGG: mex:Mext_4575 hypothetical protein. | 0.455 |
M446_6288 | dinB | M446_6288 | M446_6682 | KEGG: pin:Ping_0445 membrane protein involved in colicin uptake-like protein. | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.455 |
M446_6288 | lexA | M446_6288 | M446_6716 | KEGG: pin:Ping_0445 membrane protein involved in colicin uptake-like protein. | Transcriptional repressor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.736 |
M446_6288 | polA | M446_6288 | M446_0678 | KEGG: pin:Ping_0445 membrane protein involved in colicin uptake-like protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.535 |
M446_6288 | recA | M446_6288 | M446_0291 | KEGG: pin:Ping_0445 membrane protein involved in colicin uptake-like protein. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.813 |
M446_6694 | M446_4497 | M446_6694 | M446_4497 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | KEGG: mex:Mext_4575 hypothetical protein. | 0.455 |
M446_6694 | dinB | M446_6694 | M446_6682 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.610 |
M446_6694 | lexA | M446_6694 | M446_6716 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Transcriptional repressor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.868 |
M446_6694 | polA | M446_6694 | M446_0678 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.535 |
M446_6694 | recA | M446_6694 | M446_0291 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.889 |
dinB | M446_6288 | M446_6682 | M446_6288 | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | KEGG: pin:Ping_0445 membrane protein involved in colicin uptake-like protein. | 0.455 |
dinB | M446_6694 | M446_6682 | M446_6694 | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.610 |
dinB | lexA | M446_6682 | M446_6716 | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Transcriptional repressor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.880 |
dinB | polA | M446_6682 | M446_0678 | DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.805 |