STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
psmAProteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (259 aa)    
Predicted Functional Partners:
pan
26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...]
 
 0.999
psmB
Proteasome endopeptidase complex; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.999
ABR66242.1
AAA family ATPase, CDC48 subfamily; KEGG: mmp:MMP0176 CDC48 cell division cycle protein family member; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein; AAA ATPase central domain protein; cell division protein 48 CDC48 domain 2; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase.
 
 0.942
ABR65231.1
PFAM: protein of unknown function DUF75; KEGG: mmq:MmarC5_0721 protein of unknown function DUF75.
   
 
 0.926
rpl40e
KEGG: mmp:MMP0151 LSU ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.921
ABR65926.1
PFAM: protein of unknown function DUF75; KEGG: mmp:MMP1611 hypothetical protein.
   
 
 0.882
rpl37ae
TIGRFAM: ribosomal protein L37a; PFAM: Ribosomal L37ae protein; KEGG: mmp:MMP0249 large subunit ribosomal protein L37Ae.
 
    0.855
rpl15e
PFAM: Ribosomal protein L15e; KEGG: mmp:MMP0298 LSU ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family.
 
  
 0.841
ABR66315.1
PFAM: Shwachman-Bodian-Diamond syndrome proteins; KEGG: mmp:MMP0250 hypothetical protein.
 
  
 0.837
rpl4
Ribosomal protein L4/L1e; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
 
 
 0.784
Your Current Organism:
Methanococcus maripaludis C7
NCBI taxonomy Id: 426368
Other names: M. maripaludis C7, Methanococcus maripaludis str. C7, Methanococcus maripaludis strain C7
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