node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHAC2 | DNAJC21 | ENSSTOP00000031288 | ENSSTOP00000008622 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. | DnaJ heat shock protein family (Hsp40) member C21. | 0.793 |
CHAC2 | PRDX6 | ENSSTOP00000031288 | ENSSTOP00000013645 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. | Peroxiredoxin 6. | 0.840 |
DNAJC1 | DNAJC21 | ENSSTOP00000002060 | ENSSTOP00000008622 | DnaJ heat shock protein family (Hsp40) member C1. | DnaJ heat shock protein family (Hsp40) member C21. | 0.708 |
DNAJC21 | CHAC2 | ENSSTOP00000008622 | ENSSTOP00000031288 | DnaJ heat shock protein family (Hsp40) member C21. | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. | 0.793 |
DNAJC21 | DNAJC1 | ENSSTOP00000008622 | ENSSTOP00000002060 | DnaJ heat shock protein family (Hsp40) member C21. | DnaJ heat shock protein family (Hsp40) member C1. | 0.708 |
DNAJC21 | EIF6 | ENSSTOP00000008622 | ENSSTOP00000011747 | DnaJ heat shock protein family (Hsp40) member C21. | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | 0.687 |
DNAJC21 | NMD3 | ENSSTOP00000008622 | ENSSTOP00000026526 | DnaJ heat shock protein family (Hsp40) member C21. | 60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. | 0.864 |
DNAJC21 | PRDX6 | ENSSTOP00000008622 | ENSSTOP00000013645 | DnaJ heat shock protein family (Hsp40) member C21. | Peroxiredoxin 6. | 0.863 |
DNAJC21 | Pa2g4 | ENSSTOP00000008622 | ENSSTOP00000006920 | DnaJ heat shock protein family (Hsp40) member C21. | Peptidase_M24 domain-containing protein. | 0.866 |
DNAJC21 | RETREG1 | ENSSTOP00000008622 | ENSSTOP00000019264 | DnaJ heat shock protein family (Hsp40) member C21. | Reticulophagy regulator 1. | 0.752 |
DNAJC21 | RETREG2 | ENSSTOP00000008622 | ENSSTOP00000032343 | DnaJ heat shock protein family (Hsp40) member C21. | Reticulophagy regulator family member 2. | 0.693 |
DNAJC21 | RETREG3 | ENSSTOP00000008622 | ENSSTOP00000003313 | DnaJ heat shock protein family (Hsp40) member C21. | Reticulophagy regulator family member 3. | 0.693 |
DNAJC21 | ZNF622 | ENSSTOP00000008622 | ENSSTOP00000000566 | DnaJ heat shock protein family (Hsp40) member C21. | Zinc finger protein 622. | 0.752 |
EIF6 | DNAJC21 | ENSSTOP00000011747 | ENSSTOP00000008622 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | DnaJ heat shock protein family (Hsp40) member C21. | 0.687 |
EIF6 | NMD3 | ENSSTOP00000011747 | ENSSTOP00000026526 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | 60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. | 0.979 |
EIF6 | Pa2g4 | ENSSTOP00000011747 | ENSSTOP00000006920 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Peptidase_M24 domain-containing protein. | 0.979 |
EIF6 | RETREG1 | ENSSTOP00000011747 | ENSSTOP00000019264 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Reticulophagy regulator 1. | 0.960 |
EIF6 | RETREG2 | ENSSTOP00000011747 | ENSSTOP00000032343 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Reticulophagy regulator family member 2. | 0.907 |
EIF6 | RETREG3 | ENSSTOP00000011747 | ENSSTOP00000003313 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Reticulophagy regulator family member 3. | 0.907 |
EIF6 | ZNF622 | ENSSTOP00000011747 | ENSSTOP00000000566 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Zinc finger protein 622. | 0.969 |