STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DMRT2Doublesex and mab-3 related transcription factor 2. (561 aa)    
Predicted Functional Partners:
KPTN
Kaptin, actin binding protein.
    
 0.736
Depdc5
DEP domain-containing protein.
    
 0.719
WDR59
WD repeat domain 59.
    
 0.716
WDR24
WD repeat domain 24.
    
 0.711
NPRL2
NPR2 like, GATOR1 complex subunit.
    
 0.707
XRCC4
X-ray repair cross complementing 4.
    
 0.660
ITFG2
Integrin alpha FG-GAP repeat containing 2.
    
 0.660
IMMP1L
Mitochondrial inner membrane protease subunit.
    
 0.660
TERT
Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...]
      
 0.600
NPRL3
NPR3 like, GATOR1 complex subunit.
     
 0.580
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.