STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAHemA; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (415 aa)    
Predicted Functional Partners:
hemL
HemL; Glutamate-1-semialdehyde 2,1-aminomutase.
 
 0.998
hemC
HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.976
hemD
HemD; Porphyrin biosynthesis protein HemD.
 
  
 0.971
gluS
GluS; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
     
 0.929
hemB
HemB; Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
  
 0.927
sirC
SirC; Predicted precorrin-2 dehydrogenase.
 
   
 0.762
CKL_1734
Predicted NRPS adenylation domain.
  
 
 0.654
CKL_2357
Predicted NRPS adenylation domain.
  
 
 0.654
cbiL
CbiL; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.
 
   
 0.633
cbiF
CbiF; Precorrin-4 C(11)-methyltransferase.
 
   
 0.584
Your Current Organism:
Clostridium kluyveri
NCBI taxonomy Id: 431943
Other names: C. kluyveri DSM 555, Clostridium kluyveri DSM 555, Clostridium kluyveri str. DSM 555, Clostridium kluyveri strain DSM 555
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.