STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trmBTrmB; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (211 aa)    
Predicted Functional Partners:
truB
TruB; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 
 0.840
CKL_1372
Hypothetical protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
 
 0.725
trmD
Hypothetical protein; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
      
 0.626
truA
TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
 
 0.611
CKL_2033
Conserved hypothetical protein.
  
  
 0.608
birA
Bifunctional BirA-related protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.607
serS
SerS; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
   
 
 0.602
rpmD
RpmD; 50S ribosomal protein L30.
   
    0.597
CKL_2812
Conserved hypothetical protein.
       0.561
CKL_0780
Predicted short-chain dehydrogenase.
  
    0.550
Your Current Organism:
Clostridium kluyveri
NCBI taxonomy Id: 431943
Other names: C. kluyveri DSM 555, Clostridium kluyveri DSM 555, Clostridium kluyveri str. DSM 555, Clostridium kluyveri strain DSM 555
Server load: high (82%) [HD]