node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CKL_0169 | CKL_1340 | CKL_0169 | CKL_1340 | Predicted stage II sporulation protein E. | Predicted sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.960 |
CKL_0169 | CKL_3154 | CKL_0169 | CKL_3154 | Predicted stage II sporulation protein E. | RNA polymerase sigma-F factor; Belongs to the sigma-70 factor family. | 0.751 |
CKL_0169 | CKL_3720 | CKL_0169 | CKL_3720 | Predicted stage II sporulation protein E. | Predicted stage II sporulation protein R. | 0.906 |
CKL_0169 | spo0A | CKL_0169 | CKL_1237 | Predicted stage II sporulation protein E. | Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.885 |
CKL_0169 | spoIIAA | CKL_0169 | CKL_3156 | Predicted stage II sporulation protein E. | SpoIIAA; Anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family. | 0.758 |
CKL_0169 | spoIIAB | CKL_0169 | CKL_3155 | Predicted stage II sporulation protein E. | SpoIIAB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.922 |
CKL_1340 | CKL_0169 | CKL_1340 | CKL_0169 | Predicted sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Predicted stage II sporulation protein E. | 0.960 |
CKL_1340 | CKL_3154 | CKL_1340 | CKL_3154 | Predicted sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | RNA polymerase sigma-F factor; Belongs to the sigma-70 factor family. | 0.672 |
CKL_1340 | CKL_3720 | CKL_1340 | CKL_3720 | Predicted sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Predicted stage II sporulation protein R. | 0.916 |
CKL_1340 | spo0A | CKL_1340 | CKL_1237 | Predicted sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.792 |
CKL_1340 | spoIIAA | CKL_1340 | CKL_3156 | Predicted sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | SpoIIAA; Anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family. | 0.790 |
CKL_1340 | spoIIAB | CKL_1340 | CKL_3155 | Predicted sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | SpoIIAB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.910 |
CKL_3154 | CKL_0169 | CKL_3154 | CKL_0169 | RNA polymerase sigma-F factor; Belongs to the sigma-70 factor family. | Predicted stage II sporulation protein E. | 0.751 |
CKL_3154 | CKL_1340 | CKL_3154 | CKL_1340 | RNA polymerase sigma-F factor; Belongs to the sigma-70 factor family. | Predicted sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.672 |
CKL_3154 | CKL_3720 | CKL_3154 | CKL_3720 | RNA polymerase sigma-F factor; Belongs to the sigma-70 factor family. | Predicted stage II sporulation protein R. | 0.687 |
CKL_3154 | spo0A | CKL_3154 | CKL_1237 | RNA polymerase sigma-F factor; Belongs to the sigma-70 factor family. | Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.779 |
CKL_3154 | spoIIAA | CKL_3154 | CKL_3156 | RNA polymerase sigma-F factor; Belongs to the sigma-70 factor family. | SpoIIAA; Anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family. | 0.970 |
CKL_3154 | spoIIAB | CKL_3154 | CKL_3155 | RNA polymerase sigma-F factor; Belongs to the sigma-70 factor family. | SpoIIAB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.992 |
CKL_3720 | CKL_0169 | CKL_3720 | CKL_0169 | Predicted stage II sporulation protein R. | Predicted stage II sporulation protein E. | 0.906 |
CKL_3720 | CKL_1340 | CKL_3720 | CKL_1340 | Predicted stage II sporulation protein R. | Predicted sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.916 |