node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CKL_0993 | cbiH | CKL_0993 | CKL_0730 | Conserved hypothetical protein. | CbiH; precorrin-3B C(17)-methyltransferase. | 0.504 |
CKL_0993 | cbiP | CKL_0993 | CKL_0721 | Conserved hypothetical protein. | CbiP; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.487 |
CKL_0993 | cobC2 | CKL_0993 | CKL_0732 | Conserved hypothetical protein. | CobC2; Alpha-ribazole phosphatase; Belongs to the phosphoglycerate mutase family. | 0.626 |
CKL_0993 | cobS | CKL_0993 | CKL_3341 | Conserved hypothetical protein. | Hypothetical protein; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.949 |
cbiB | cbiC | CKL_0722 | CKL_0723 | CbiB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiC; precorrin-8X methylmutase. | 0.999 |
cbiB | cbiH | CKL_0722 | CKL_0730 | CbiB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiH; precorrin-3B C(17)-methyltransferase. | 0.980 |
cbiB | cbiP | CKL_0722 | CKL_0721 | CbiB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CbiP; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.996 |
cbiB | cobC2 | CKL_0722 | CKL_0732 | CbiB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobC2; Alpha-ribazole phosphatase; Belongs to the phosphoglycerate mutase family. | 0.559 |
cbiB | cobD2 | CKL_0722 | CKL_2910 | CbiB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobD2; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.943 |
cbiB | cobO | CKL_0722 | CKL_0715 | CbiB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobO; cob(I)yrinic acid a,c-diamide adenosyltransferase. | 0.986 |
cbiB | cobS | CKL_0722 | CKL_3341 | CbiB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Hypothetical protein; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.903 |
cbiB | cobT | CKL_0722 | CKL_2908 | CbiB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobT; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.963 |
cbiB | cobU | CKL_0722 | CKL_0731 | CbiB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobU; Bifunctional adenosylcobalamin biosynthesis protein CobU. | 0.969 |
cbiC | cbiB | CKL_0723 | CKL_0722 | CbiC; precorrin-8X methylmutase. | CbiB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.999 |
cbiC | cbiH | CKL_0723 | CKL_0730 | CbiC; precorrin-8X methylmutase. | CbiH; precorrin-3B C(17)-methyltransferase. | 0.998 |
cbiC | cbiP | CKL_0723 | CKL_0721 | CbiC; precorrin-8X methylmutase. | CbiP; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.999 |
cbiC | cobC2 | CKL_0723 | CKL_0732 | CbiC; precorrin-8X methylmutase. | CobC2; Alpha-ribazole phosphatase; Belongs to the phosphoglycerate mutase family. | 0.756 |
cbiC | cobD2 | CKL_0723 | CKL_2910 | CbiC; precorrin-8X methylmutase. | CobD2; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.938 |
cbiC | cobO | CKL_0723 | CKL_0715 | CbiC; precorrin-8X methylmutase. | CobO; cob(I)yrinic acid a,c-diamide adenosyltransferase. | 0.814 |
cbiC | cobS | CKL_0723 | CKL_3341 | CbiC; precorrin-8X methylmutase. | Hypothetical protein; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.905 |