STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KAFR0F02490Histone H2A; Belongs to the histone H2A family. (132 aa)    
Predicted Functional Partners:
KAFR0J01290
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 0.999
KAFR0F04130
Uncharacterized protein.
   
 
 0.990
KAFR0H02000
Ubiquitin-like domain-containing protein.
   
 0.988
KAFR0J01300
Histone H3; Belongs to the histone H3 family.
 
 
 0.987
KAFR0A05230
Histone H2A; Belongs to the histone H2A family.
  
0.983
KAFR0C00770
Histone H2B; Belongs to the histone H2B family.
 
 0.980
KAFR0F02480
Histone H2B; Belongs to the histone H2B family.
 
 0.980
KAFR0F01770
Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
    
 0.959
KAFR0A03290
Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.
    
 
 0.937
KAFR0F01160
RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
    
 0.919
Your Current Organism:
Kazachstania africana
NCBI taxonomy Id: 1071382
Other names: K. africana CBS 2517, Kazachstania africana CBS 2517
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