STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IF1G_03718Phosphatidylinositol 3,5-bisphosphate-binding protein. (378 aa)    
Predicted Functional Partners:
IF1G_10171
Autophagy regulatory protein Atg2.
    
 
 0.766
IF1G_09827
Protein-vacuolar targeting protein Atg18.
   
0.705
IF1G_07868
WD domain, g-beta repeat domain-containing protein.
   
 0.639
IF1G_05974
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
    
 
 0.616
IF1G_02392
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
   
  
 0.530
IF1G_00651
Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
      
 0.501
IF1G_01083
Autophagy-related protein 3.
   
  
 0.498
IF1G_03160
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.
      
 0.497
IF1G_00376
Serine/threonine protein kinase (Pdd7p).
      
 0.491
IF1G_06583
DUF1649 domain-containing protein.
      
 0.477
Your Current Organism:
Cordyceps javanica
NCBI taxonomy Id: 43265
Other names: C. javanica, CBS 134.22, Cordyceps javanica (Frieder. & Bally) Kepler, B. Shrestha & Spatafora, 2017, Isaria javanica, Isaria javanicus, Paecilomyces javanica, Paecilomyces sp. ARSEF 3776, Paecilomyces sp. ARSEF 3778, Spicaria javanica
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