STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speAPutative arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. (630 aa)    
Predicted Functional Partners:
BVU_3224
Conserved hypothetical protein; Belongs to the agmatine deiminase family.
 
  
 0.955
argB
Putative acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
     
 0.873
argH
Argininosuccinate lyase.
     
 0.829
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.804
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
       0.780
BVU_1339
RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
       0.751
BVU_1340
Conserved hypothetical protein.
       0.751
BVU_1333
Conserved hypothetical protein.
  
    0.477
BVU_1080
Putative ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase H family.
       0.454
BVU_1605
Nitroreductase.
       0.454
Your Current Organism:
Bacteroides vulgatus
NCBI taxonomy Id: 435590
Other names: B. vulgatus ATCC 8482, Bacteroides vulgatus ATCC 8482, Bacteroides vulgatus str. ATCC 8482, Bacteroides vulgatus strain ATCC 8482
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.