node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BVU_0338 | hisD | BVU_0338 | BVU_2362 | Histidine ammonia-lyase. | Putative histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.917 |
BVU_0886 | hisA | BVU_0886 | BVU_3852 | Hemolysin erythrocyte lysis protein 2. | Imidazole-4-carboxamide isomerase. | 0.639 |
BVU_0886 | hisB | BVU_0886 | BVU_2364 | Hemolysin erythrocyte lysis protein 2. | Histidine biosynthesis bifunctional protein HisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.956 |
BVU_0886 | hisD | BVU_0886 | BVU_2362 | Hemolysin erythrocyte lysis protein 2. | Putative histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.696 |
BVU_0886 | hisF | BVU_0886 | BVU_3853 | Hemolysin erythrocyte lysis protein 2. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.702 |
BVU_0886 | hisG | BVU_0886 | BVU_2361 | Hemolysin erythrocyte lysis protein 2. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.697 |
BVU_0886 | hisH | BVU_0886 | BVU_3851 | Hemolysin erythrocyte lysis protein 2. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.710 |
BVU_0886 | hisI | BVU_0886 | BVU_3854 | Hemolysin erythrocyte lysis protein 2. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family. | 0.961 |
BVU_3116 | hisA | BVU_3116 | BVU_3852 | Putative histidinol-phosphate aminotransferase. | Imidazole-4-carboxamide isomerase. | 0.728 |
BVU_3116 | hisB | BVU_3116 | BVU_2364 | Putative histidinol-phosphate aminotransferase. | Histidine biosynthesis bifunctional protein HisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.964 |
BVU_3116 | hisD | BVU_3116 | BVU_2362 | Putative histidinol-phosphate aminotransferase. | Putative histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.794 |
BVU_3116 | hisF | BVU_3116 | BVU_3853 | Putative histidinol-phosphate aminotransferase. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.765 |
BVU_3116 | hisG | BVU_3116 | BVU_2361 | Putative histidinol-phosphate aminotransferase. | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. | 0.750 |
BVU_3116 | hisH | BVU_3116 | BVU_3851 | Putative histidinol-phosphate aminotransferase. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.787 |
BVU_3116 | hisI | BVU_3116 | BVU_3854 | Putative histidinol-phosphate aminotransferase. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; In the N-terminal section; belongs to the PRA-CH family. | 0.962 |
hisA | BVU_0886 | BVU_3852 | BVU_0886 | Imidazole-4-carboxamide isomerase. | Hemolysin erythrocyte lysis protein 2. | 0.639 |
hisA | BVU_3116 | BVU_3852 | BVU_3116 | Imidazole-4-carboxamide isomerase. | Putative histidinol-phosphate aminotransferase. | 0.728 |
hisA | hisB | BVU_3852 | BVU_2364 | Imidazole-4-carboxamide isomerase. | Histidine biosynthesis bifunctional protein HisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.992 |
hisA | hisC | BVU_3852 | BVU_2363 | Imidazole-4-carboxamide isomerase. | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.869 |
hisA | hisD | BVU_3852 | BVU_2362 | Imidazole-4-carboxamide isomerase. | Putative histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.980 |