STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A167UPD8ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (701 aa)    
Predicted Functional Partners:
A0A166WIK2
PIN domain-like protein.
  
 0.932
A0A166AJR0
Dna2-domain-containing protein.
   
 0.914
A0A166IHG8
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
 0.914
A0A166WIJ1
Uncharacterized protein.
  
 0.903
A0A166NBG7
Rad51 domain-containing protein.
  
 0.897
A0A166K509
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.895
A0A166WH72
Recombination protein Rad52.
   
 0.893
A0A165YU28
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
   
 0.888
A0A166FX61
P-loop containing nucleoside triphosphate hydrolase protein.
   
 0.884
A0A166QMR6
P-loop containing nucleoside triphosphate hydrolase protein.
  
 0.883
Your Current Organism:
Fibularhizoctonia sp. CBS109695
NCBI taxonomy Id: 436010
Other names: F. sp. CBS 109695, Fibularhizoctonia sp. CBS 109695, Fibulorhizoctonia sp. CBS 109695
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