STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (324 aa)    
Predicted Functional Partners:
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: drm:Dred_2902 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.986
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
   
  
 0.949
fbp
PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: vch:VC2544 fructose-1,6-bisphosphatase.
    
 0.927
aroA-2
Predicted phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.
    
 0.924
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 
 0.923
ACD66026.1
KEGG: ppd:Ppro_1852 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
 
 
 0.922
ACD65979.1
PFAM: Transketolase domain protein; KEGG: tpd:Teth39_0491 transketolase domain protein.
    
  0.903
ACD65978.1
PFAM: Transketolase central region; Transketolase domain protein; KEGG: cdf:CD3459 transketolase, pyridine binding subunit.
    
  0.902
tpiA
Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
  
 0.874
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
  
 0.868
Your Current Organism:
Sulfurihydrogenibium sp. YO3AOP1
NCBI taxonomy Id: 436114
Other names: S. sp. YO3AOP1
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