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priS protein (Nitrosopumilus maritimus) - STRING interaction network
"priS" - DNA primase small subunit PriS in Nitrosopumilus maritimus
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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priSDNA primase small subunit PriS; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthe [...] (373 aa)    
Predicted Functional Partners:
priL
DNA primase large subunit PriL; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair (341 aa)
 
 
  0.999
pcn
DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (248 aa)
   
   
  0.985
polB
DNA polymerase II small subunit; Possesses two activities- a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3’ to 5’ direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family (481 aa)
     
 
  0.969
Nmar_0948
PFAM- DNA polymerase B exonuclease; DNA polymerase B region; SMART- DNA-directed DNA polymerase B; KEGG- tpe-Tpen_0298 DNA polymerase B region (852 aa)
   
 
  0.963
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA- DNA hybrids; Belongs to the RNase HII family (205 aa)
     
   
  0.943
Nmar_1627
Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen (884 aa)
     
   
  0.941
csl4
Exosome complex component Csl4; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs (183 aa)
 
     
  0.893
Nmar_0077
PFAM- RNA binding S1 domain protein; translation initiation factor 2, alpha subunit; KEGG- rci-LRC294 translation initiation factor 2, alpha subunit (265 aa)
 
   
  0.885
Nmar_0270
PFAM- AAA ATPase central domain protein; SMART- AAA ATPase; KEGG- mth-MTH240 replication factor C, large subunit (385 aa)
   
 
  0.884
Nmar_0240
Replication factor C; PFAM- AAA ATPase central domain protein; Replication factor C; SMART- AAA ATPase; KEGG- smr-Smar_1225 replication factor C (316 aa)
   
 
  0.878
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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