STRINGSTRING
cbiA protein (Nitrosopumilus maritimus) - STRING interaction network
"cbiA" - Cobyrinate a,c-diamide synthase in Nitrosopumilus maritimus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbiACobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family (450 aa)    
Predicted Functional Partners:
Nmar_0080
PFAM- Precorrin-8X methylmutase CbiC/CobH; KEGG- lic-LIC20131 precorrin isomerase (213 aa)
 
  0.995
cobQ
Probable cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (279 aa)
   
  0.992
cbiT
Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating); Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 (196 aa)
   
  0.989
cobD
Probable cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (323 aa)
   
  0.984
Nmar_0058
TIGRFAM- precorrin-2 C20-methyltransferase; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG- gsu-GSU2995 precorrin-2 C20-methyltransferase (240 aa)
   
  0.982
cobS
Adenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5’-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5’-phosphate; Belongs to the CobS family (241 aa)
 
   
  0.940
Nmar_1752
TIGRFAM- precorrin-3B C17-methyltransferase; PFAM- Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG- gtn-GTNG_1694 precorrin-3 methylase (264 aa)
   
  0.921
Nmar_0082
PFAM- cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG- gtn-GTNG_1686 cobalamin biosynthesis protein CbiG (350 aa)
   
  0.910
cbiD
Cobalt-precorrin-5B C(1)-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A (361 aa)
   
  0.907
Nmar_0078
TIGRFAM- cob(I)alamin adenosyltransferase; PFAM- ATP-corrinoid adenosyltransferase BtuR/CobO/CobP; KEGG- pth-PTH_0071 ATP-corrinoid adenosyltransferase (176 aa)
 
   
  0.884
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
Server load: low (11%) [HD]