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Nmar_0095 protein (Nitrosopumilus maritimus) - STRING interaction network
"Nmar_0095" - Protein GrpE in Nitrosopumilus maritimus
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Nmar_0095Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- dependent [...] (187 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein DnaK; Acts as a chaperone (636 aa)
   
 
  0.999
Nmar_0097
TIGRFAM- chaperone protein DnaJ; PFAM- DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG- mbu-Mbur_1311 chaperone DnaJ (361 aa)
 
 
  0.911
Nmar_1024
PFAM- heat shock protein DnaJ domain protein; KEGG- cfa-609460 DnaJ (Hsp40) homolog, subfamily B, member 8 (223 aa)
 
 
  0.841
Nmar_0094
annotation not available (379 aa)
              0.740
Nmar_1792
TIGRFAM- thermosome; PFAM- chaperonin Cpn60/TCP-1; KEGG- mbn-Mboo_0199 thermosome (570 aa)
   
 
  0.686
Nmar_1577
TIGRFAM- thermosome; PFAM- chaperonin Cpn60/TCP-1; KEGG- pfu-PF1974 thermosome, single subunit (540 aa)
   
 
  0.686
Nmar_0098
KEGG- cbh-CLC_1260 hypothetical protein (177 aa)
              0.679
Nmar_1767
PFAM- heat shock protein DnaJ domain protein; KEGG- cfa-611441 similar to DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4) (DnaJ protein homolog 2) (HSJ-2) (HSDJ) (384 aa)
   
 
  0.677
Nmar_0737
PFAM- heat shock protein DnaJ domain protein; KEGG- mga-MGA_0877 molecular chaperones (contain C-terminal Zn finger domain) (182 aa)
   
 
  0.677
hisB
PFAM- imidazoleglycerol-phosphate dehydratase; KEGG- hne-HNE_0073 imidazoleglycerol phosphate dehydratase (195 aa)
   
   
  0.620
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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