STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhLactate/malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. (304 aa)    
Predicted Functional Partners:
Nmar_1099
KEGG: sfu:Sfum_2105 citrate (Si)-synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase.
  
 0.980
Nmar_0546
PFAM: Chorismate mutase; aminotransferase class I and II; KEGG: tpt:Tpet_1516 aminotransferase, class I and II.
  
 0.937
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
  
 
 0.922
Nmar_0865
PFAM: aminotransferase class I and II; KEGG: mhu:Mhun_1459 aminotransferase, class I and II.
  
 0.921
Nmar_0676
PFAM: Lactate/malate dehydrogenase; KEGG: cho:Chro.70063 lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
  
 
0.911
Nmar_1455
TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mja:MJ0929 adenylosuccinate lyase.
  
 0.853
argH
KEGG: mtp:Mthe_0492 argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase.
  
 0.846
Nmar_0958
PFAM: cobalamin B12-binding domain protein; KEGG: tte:TTE2388 methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding).
    
 0.826
Nmar_0954
KEGG: tte:TTE1217 Methylmalonyl-CoA mutase, N-terminal domain/subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase.
    
 0.825
Nmar_1260
PFAM: fumarate lyase; KEGG: aba:Acid345_2689 fumarate lyase.
    
 0.807
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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