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aroC protein (Nitrosopumilus maritimus) - STRING interaction network
"aroC" - Chorismate synthase in Nitrosopumilus maritimus
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system (365 aa)    
Predicted Functional Partners:
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate (422 aa)
 
 
  0.994
Nmar_0546
Aminotransferase; PFAM- Chorismate mutase; aminotransferase class I and II; KEGG- tpt-Tpet_1516 aminotransferase, class I and II (456 aa)
   
 
  0.992
aroE
Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) (273 aa)
 
  0.988
Nmar_0912
TIGRFAM- glutamine amidotransferase of anthranilate synthase; PFAM- glutamine amidotransferase class-I; KEGG- cac-CAC3162 putative anthranilate synthase component II (198 aa)
 
 
  0.963
Nmar_0911
PFAM- Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG- mst-Msp_1070 TrpE (449 aa)
 
 
  0.963
Nmar_0545
PFAM- Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG- mba-Mbar_A0924 prephenate dehydrogenase (283 aa)
   
   
  0.961
aroD
3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate; Belongs to the type-I 3-dehydroquinase family (223 aa)
 
 
  0.913
Nmar_0544
PFAM- NUDIX hydrolase; KEGG- det-DET1290 NUDIX domain protein (134 aa)
   
      0.867
mqnA
Chorismate dehydratase; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) (253 aa)
       
    0.823
aroK
TIGRFAM- shikimate kinase; PFAM- GHMP kinase; KEGG- mae-Maeo_0247 shikimate kinase (284 aa)
 
     
  0.815
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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