node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Nmar_0545 | Nmar_0546 | Nmar_0545 | Nmar_0546 | PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mba:Mbar_A0924 prephenate dehydrogenase. | PFAM: Chorismate mutase; aminotransferase class I and II; KEGG: tpt:Tpet_1516 aminotransferase, class I and II. | 0.999 |
Nmar_0545 | Nmar_1567 | Nmar_0545 | Nmar_1567 | PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mba:Mbar_A0924 prephenate dehydrogenase. | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | 0.990 |
Nmar_0545 | aroA | Nmar_0545 | Nmar_0548 | PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mba:Mbar_A0924 prephenate dehydrogenase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.768 |
Nmar_0545 | aroA-2 | Nmar_0545 | Nmar_0553 | PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mba:Mbar_A0924 prephenate dehydrogenase. | Predicted phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. | 0.401 |
Nmar_0545 | aroB | Nmar_0545 | Nmar_0552 | PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mba:Mbar_A0924 prephenate dehydrogenase. | 3-dehydroquinate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. | 0.552 |
Nmar_0545 | aroC | Nmar_0545 | Nmar_0547 | PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mba:Mbar_A0924 prephenate dehydrogenase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.984 |
Nmar_0545 | aroD | Nmar_0545 | Nmar_0551 | PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mba:Mbar_A0924 prephenate dehydrogenase. | 3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.553 |
Nmar_0545 | aroE | Nmar_0545 | Nmar_0550 | PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mba:Mbar_A0924 prephenate dehydrogenase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.651 |
Nmar_0545 | aroK | Nmar_0545 | Nmar_0549 | PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mba:Mbar_A0924 prephenate dehydrogenase. | TIGRFAM: shikimate kinase; PFAM: GHMP kinase; KEGG: mae:Maeo_0247 shikimate kinase. | 0.584 |
Nmar_0546 | Nmar_0545 | Nmar_0546 | Nmar_0545 | PFAM: Chorismate mutase; aminotransferase class I and II; KEGG: tpt:Tpet_1516 aminotransferase, class I and II. | PFAM: Prephenate dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: mba:Mbar_A0924 prephenate dehydrogenase. | 0.999 |
Nmar_0546 | Nmar_1078 | Nmar_0546 | Nmar_1078 | PFAM: Chorismate mutase; aminotransferase class I and II; KEGG: tpt:Tpet_1516 aminotransferase, class I and II. | PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: sfu:Sfum_2464 deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase. | 0.434 |
Nmar_0546 | Nmar_1567 | Nmar_0546 | Nmar_1567 | PFAM: Chorismate mutase; aminotransferase class I and II; KEGG: tpt:Tpet_1516 aminotransferase, class I and II. | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: det:DET0461 chorismate mutase / prephenate dehydratase. | 0.998 |
Nmar_0546 | aroA | Nmar_0546 | Nmar_0548 | PFAM: Chorismate mutase; aminotransferase class I and II; KEGG: tpt:Tpet_1516 aminotransferase, class I and II. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.976 |
Nmar_0546 | aroA-2 | Nmar_0546 | Nmar_0553 | PFAM: Chorismate mutase; aminotransferase class I and II; KEGG: tpt:Tpet_1516 aminotransferase, class I and II. | Predicted phospho-2-dehydro-3-deoxyheptonate aldolase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. | 0.609 |
Nmar_0546 | aroB | Nmar_0546 | Nmar_0552 | PFAM: Chorismate mutase; aminotransferase class I and II; KEGG: tpt:Tpet_1516 aminotransferase, class I and II. | 3-dehydroquinate synthase; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. | 0.788 |
Nmar_0546 | aroC | Nmar_0546 | Nmar_0547 | PFAM: Chorismate mutase; aminotransferase class I and II; KEGG: tpt:Tpet_1516 aminotransferase, class I and II. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.998 |
Nmar_0546 | aroD | Nmar_0546 | Nmar_0551 | PFAM: Chorismate mutase; aminotransferase class I and II; KEGG: tpt:Tpet_1516 aminotransferase, class I and II. | 3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.879 |
Nmar_0546 | aroE | Nmar_0546 | Nmar_0550 | PFAM: Chorismate mutase; aminotransferase class I and II; KEGG: tpt:Tpet_1516 aminotransferase, class I and II. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.891 |
Nmar_0546 | aroK | Nmar_0546 | Nmar_0549 | PFAM: Chorismate mutase; aminotransferase class I and II; KEGG: tpt:Tpet_1516 aminotransferase, class I and II. | TIGRFAM: shikimate kinase; PFAM: GHMP kinase; KEGG: mae:Maeo_0247 shikimate kinase. | 0.592 |
Nmar_1078 | Nmar_0546 | Nmar_1078 | Nmar_0546 | PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: sfu:Sfum_2464 deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase. | PFAM: Chorismate mutase; aminotransferase class I and II; KEGG: tpt:Tpet_1516 aminotransferase, class I and II. | 0.434 |