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purQ protein (Nitrosopumilus maritimus) - STRING interaction network
"purQ" - Phosphoribosylformylglycinamidine synthase subunit PurQ in Nitrosopumilus maritimus
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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purQPhosphoribosylformylglycinamidine synthase subunit PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (228 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycinamidine synthase subunit PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (721 aa)
  0.999
purM
KEGG- msi-Msm_1039 phosphoribosylformylglycinamidine cyclo-ligase (AirS), PurM; TIGRFAM- phosphoribosylformylglycinamidine cyclo-ligase; PFAM- AIR synthase related protein; AIR synthase related protein domain protein (340 aa)
  0.998
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine (489 aa)
 
   
  0.989
purS
Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (86 aa)
     
  0.980
Nmar_1114
TIGRFAM- phosphoribosylglycinamide formyltransferase; PFAM- formyl transferase domain protein; KEGG- gme-Gmet_1845 phosphoribosylglycinamide formyltransferase (191 aa)
 
 
  0.969
purD
KEGG- cbd-COXBU7E912_1753 phosphoribosylamine--glycine ligase; TIGRFAM- phosphoribosylamine--glycine ligase; PFAM- phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; ATP-grasp domain protein; Belongs to the GARS family (421 aa)
 
  0.967
purC
PFAM- SAICAR synthetase; KEGG- cjk-jk0350 phosphoribosylaminoimidazole-succinocarboxamide synthase (274 aa)
   
   
  0.958
purK
N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) (380 aa)
 
   
  0.893
Nmar_0782
PFAM- protein of unknown function DUF427; KEGG- nfa-nfa19250 hypothetical protein (92 aa)
              0.847
Nmar_1455
TIGRFAM- adenylosuccinate lyase; PFAM- fumarate lyase; KEGG- mja-MJ0929 adenylosuccinate lyase (453 aa)
 
   
  0.837
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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