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purL protein (Nitrosopumilus maritimus) - STRING interaction network
"purL" - Phosphoribosylformylglycinamidine synthase subunit PurL in Nitrosopumilus maritimus
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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purLPhosphoribosylformylglycinamidine synthase subunit PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (721 aa)    
Predicted Functional Partners:
purQ
Phosphoribosylformylglycinamidine synthase subunit PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (228 aa)
  0.999
purD
KEGG- cbd-COXBU7E912_1753 phosphoribosylamine--glycine ligase; TIGRFAM- phosphoribosylamine--glycine ligase; PFAM- phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; ATP-grasp domain protein; Belongs to the GARS family (421 aa)
 
  0.999
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine (489 aa)
 
 
  0.999
Nmar_1114
TIGRFAM- phosphoribosylglycinamide formyltransferase; PFAM- formyl transferase domain protein; KEGG- gme-Gmet_1845 phosphoribosylglycinamide formyltransferase (191 aa)
 
  0.997
purM
KEGG- msi-Msm_1039 phosphoribosylformylglycinamidine cyclo-ligase (AirS), PurM; TIGRFAM- phosphoribosylformylglycinamidine cyclo-ligase; PFAM- AIR synthase related protein; AIR synthase related protein domain protein (340 aa)
 
0.990
purC
PFAM- SAICAR synthetase; KEGG- cjk-jk0350 phosphoribosylaminoimidazole-succinocarboxamide synthase (274 aa)
 
 
  0.989
purS
Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (86 aa)
     
  0.980
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (507 aa)
   
   
  0.946
Nmar_1455
TIGRFAM- adenylosuccinate lyase; PFAM- fumarate lyase; KEGG- mja-MJ0929 adenylosuccinate lyase (453 aa)
 
 
  0.934
purE
N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (191 aa)
 
   
  0.892
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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