STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Nmar_0858TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: rrs:RoseRS_1980 ATP--cobalamin adenosyltransferase. (178 aa)    
Predicted Functional Partners:
Nmar_0078
TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; KEGG: pth:PTH_0071 ATP:corrinoid adenosyltransferase.
    
 0.949
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
    
 0.936
cobQ
Cobyrinic acid ac-diamide synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 
 0.930
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
    
 0.926
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
    
 0.926
Nmar_0859
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: rno:361462 HD domain containing 2 (predicted).
       0.596
Nmar_0860
Hypothetical protein.
       0.596
Nmar_0322
PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; KEGG: afu:AF0276 hypothetical protein; Belongs to the UPF0284 family.
     
 0.441
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.