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ilvD protein (Nitrosopumilus maritimus) - STRING interaction network
"ilvD" - KEGG: sto:ST2172 dihydroxy-acid dehydratase in Nitrosopumilus maritimus
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
ilvDKEGG- sto-ST2172 dihydroxy-acid dehydratase; TIGRFAM- dihydroxy-acid dehydratase; PFAM- dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family (558 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate; Belongs to the ketol-acid reductoisomerase family (332 aa)
 
  0.995
Nmar_1072
TIGRFAM- acetolactate synthase, large subunit, biosynthetic type; PFAM- thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG- pfu-PF0935 acetolactate synthase large subunit (566 aa)
 
  0.975
Nmar_0248
Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family (305 aa)
   
  0.959
Nmar_0192
Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family (304 aa)
   
  0.959
Nmar_1070
TIGRFAM- isopropylmalate/citramalate/homocitrate synthase; PFAM- pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG- mka-MK0391 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family (505 aa)
 
 
  0.941
Nmar_1293
PFAM- pyruvate carboxyltransferase; KEGG- mka-MK1209 2-isopropylmalate synthase (393 aa)
 
 
  0.940
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family (279 aa)
     
 
  0.933
Nmar_1071
TIGRFAM- acetolactate synthase, small subunit; PFAM- amino acid-binding ACT domain protein; KEGG- mja-MJ0161 acetolactate synthase small subunit (161 aa)
 
 
  0.810
Nmar_0546
Aminotransferase; PFAM- Chorismate mutase; aminotransferase class I and II; KEGG- tpt-Tpet_1516 aminotransferase, class I and II (456 aa)
         
  0.809
Nmar_1586
KEGG- mxa-MXAN_3050 aspartate-semialdehyde dehydrogenase; TIGRFAM- aspartate-semialdehyde dehydrogenase; PFAM- Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region (358 aa)
   
   
  0.706
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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