STRINGSTRING
trpD protein (Nitrosopumilus maritimus) - STRING interaction network
"trpD" - Anthranilate phosphoribosyltransferase in Nitrosopumilus maritimus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5’-phosphoribosyl)-anthranilate (PRA) (348 aa)    
Predicted Functional Partners:
Nmar_0914
PFAM- Indole-3-glycerol phosphate synthase; KEGG- cth-Cthe_0872 indole-3-glycerol-phosphate synthase (258 aa)
 
  0.999
Nmar_0912
TIGRFAM- glutamine amidotransferase of anthranilate synthase; PFAM- glutamine amidotransferase class-I; KEGG- cac-CAC3162 putative anthranilate synthase component II (198 aa)
 
  0.999
Nmar_0911
PFAM- Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG- mst-Msp_1070 TrpE (449 aa)
 
  0.999
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate; Belongs to the TrpA family (268 aa)
   
  0.998
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (395 aa)
   
  0.993
Nmar_0546
Aminotransferase; PFAM- Chorismate mutase; aminotransferase class I and II; KEGG- tpt-Tpet_1516 aminotransferase, class I and II (456 aa)
   
   
  0.948
Nmar_1418
TIGRFAM- orotidine 5’-phosphate decarboxylase; PFAM- Orotidine 5’-phosphate decarboxylase; KEGG- mma-MM_2083 orotidine 5’-phosphate decarboxylase (246 aa)
           
  0.651
Nmar_0299
PFAM- ribulose-phosphate 3-epimerase; Transketolase domain protein; KEGG- pth-PTH_2750 transketolase, N-terminal subunit (555 aa)
         
  0.621
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system (365 aa)
   
   
  0.619
Nmar_1267
PFAM- dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; Vitamin B12 dependent methionine synthase activation region; cobalamin B12-binding domain protein; KEGG- rrs-RoseRS_0064 methionine synthase (832 aa)
         
  0.618
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
Server load: low (22%) [HD]