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uvrA protein (Nitrosopumilus maritimus) - STRING interaction network
"uvrA" - UvrABC system protein A in Nitrosopumilus maritimus
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
uvrAUvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (939 aa)    
Predicted Functional Partners:
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (650 aa)
 
 
  0.996
Nmar_1103
TIGRFAM- excinuclease ABC, C subunit; PFAM- Excinuclease ABC C subunit domain protein; excinuclease ABC C subunit domain protein; UvrB/UvrC protein; KEGG- mmp-MMP0728 excinuclease ABC subunit C (528 aa)
 
 
  0.991
Nmar_1245
PFAM- SMC domain protein; KEGG- sto-ST2108 hypothetical purine NTPase (693 aa)
   
   
  0.885
Nmar_1106
PFAM- pyridoxamine 5’-phosphate oxidase-related FMN-binding; KEGG- sun-SUN_0949 hypothetical protein (216 aa)
              0.691
radA
DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (388 aa)
   
   
  0.627
dnaK
Chaperone protein DnaK; Acts as a chaperone (636 aa)
   
     
  0.594
Nmar_1713
PFAM- ABC transporter related; SMART- AAA ATPase; KEGG- mac-MA1668 lipoprotein releasing system, ATP-binding protein (207 aa)
   
     
  0.580
Nmar_1267
PFAM- dihydropteroate synthase DHPS; Methionine synthase B12-binding module cap domain protein; Vitamin B12 dependent methionine synthase activation region; cobalamin B12-binding domain protein; KEGG- rrs-RoseRS_0064 methionine synthase (832 aa)
         
  0.569
Nmar_0097
TIGRFAM- chaperone protein DnaJ; PFAM- DnaJ central domain protein; heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG- mbu-Mbur_1311 chaperone DnaJ (361 aa)
   
 
  0.561
Nmar_1262
PFAM- Tubulin/FtsZ GTPase; KEGG- mka-MK0821 ftsZ GTPase involved in cell division (316 aa)
       
 
  0.554
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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