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uvrB protein (Nitrosopumilus maritimus) - STRING interaction network
"uvrB" - UvrABC system protein B in Nitrosopumilus maritimus
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
uvrBUvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (650 aa)    
Predicted Functional Partners:
uvrA
UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (939 aa)
 
 
  0.996
Nmar_1103
TIGRFAM- excinuclease ABC, C subunit; PFAM- Excinuclease ABC C subunit domain protein; excinuclease ABC C subunit domain protein; UvrB/UvrC protein; KEGG- mmp-MMP0728 excinuclease ABC subunit C (528 aa)
 
  0.996
Nmar_1106
PFAM- pyridoxamine 5’-phosphate oxidase-related FMN-binding; KEGG- sun-SUN_0949 hypothetical protein (216 aa)
              0.709
Nmar_1548
PFAM- UBA/THIF-type NAD/FAD binding protein; thiamineS protein; MoeZ/MoeB domain protein; KEGG- wsu-WS1006 molybdopterin biosynthesis protein MoeB (443 aa)
 
     
  0.626
dnaK
Chaperone protein DnaK; Acts as a chaperone (636 aa)
 
     
  0.604
Nmar_0546
Aminotransferase; PFAM- Chorismate mutase; aminotransferase class I and II; KEGG- tpt-Tpet_1516 aminotransferase, class I and II (456 aa)
         
  0.603
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (440 aa)
         
  0.581
ftsY
Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) (513 aa)
 
     
  0.580
srp54
Signal recognition particle 54 kDa protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY; Belongs to the GTP-binding SRP family. SRP54 subfamily (442 aa)
 
   
  0.545
pgk
PFAM- phosphoglycerate kinase; KEGG- mja-MJ0641 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family (408 aa)
 
     
  0.526
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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