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flpA protein (Nitrosopumilus maritimus) - STRING interaction network
"flpA" - Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase in Nitrosopumilus maritimus
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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flpAFibrillarin-like rRNA/tRNA 2’-O-methyltransferase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2’-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA (224 aa)    
Predicted Functional Partners:
Nmar_1391
PFAM- Pre-mRNA processing ribonucleoprotein, binding domain protein; NOSIC domain protein; KEGG- smr-Smar_1256 pre-mRNA processing ribonucleoprotein, binding region (470 aa)
 
 
  0.999
rpl7ae
50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C’/D’ sRNAs (128 aa)
   
 
  0.999
Nmar_1394
PFAM- N2N2-dimethylguanosine tRNA methyltransferase; KEGG- msi-Msm_1031 N2,N2-dimethylguanosine tRNA methyltransferase, Trm1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family (382 aa)
 
      0.809
truB
Probable tRNA pseudouridine synthase B; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs (332 aa)
 
 
  0.803
eif6
Translation initiation factor 6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex (221 aa)
   
 
  0.774
Nmar_1381
PFAM- ribosomal RNA adenine methylase transferase; KEGG- tpt-Tpet_1357 dimethyladenosine transferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family (234 aa)
   
 
  0.771
rps15
PFAM- ribosomal protein S15; Ribosomal S13S15 domain protein; KEGG- pis-Pisl_0780 ribosomal S13S15-like protein (149 aa)
 
 
  0.764
rpl10
50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors (288 aa)
   
 
  0.743
infB
Probable translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (593 aa)
 
 
  0.723
Nmar_1387
annotation not available (60 aa)
              0.722
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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