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top6A protein (Nitrosopumilus maritimus) - STRING interaction network
"top6A" - Type 2 DNA topoisomerase 6 subunit A in Nitrosopumilus maritimus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
top6AType 2 DNA topoisomerase 6 subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family (370 aa)    
Predicted Functional Partners:
top6B
Type 2 DNA topoisomerase 6 subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity (626 aa)
 
 
  0.999
Nmar_1409
PFAM- KH type 1 domain protein; SMART- KH domain protein; KEGG- mka-MK0513 predicted RNA-binding protein containing KH domain) (190 aa)
 
        0.950
Nmar_1410
PFAM- protein of unknown function RIO1; KEGG- rci-LRC287 putative serine/threonine protein kinase (259 aa)
              0.921
radA
DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules (388 aa)
     
 
  0.808
fen
Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. Binds the unpaired 3’-DNA end and kinks the DNA to facilitate 5’ cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (340 aa)
   
 
  0.782
Nmar_1309
PFAM- CoA-binding domain protein; ATP-grasp domain protein; KEGG- mem-Memar_2327 CoA-binding domain protein (705 aa)
       
      0.753
Nmar_0206
PFAM- CoA-binding domain protein; KEGG- rci-RCIX831 acetyl-CoA synthetase (ADP-forming), alpha and beta subunit fusion (698 aa)
       
      0.753
Nmar_1412
PFAM- Translation initiation factor IF2/IF5; KEGG- pab-PAB0959 translation initiation factor aIF-2 beta subunit (140 aa)
 
        0.742
pcn
DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (248 aa)
   
   
  0.699
dnaG
DNA primase DnaG; SMART- Toprim sub domain protein; KEGG- sso-SSO0079 Bacterial-like DNA primase (380 aa)
   
     
  0.672
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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