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guaA protein (Nitrosopumilus maritimus) - STRING interaction network
"guaA" - GMP synthase [glutamine-hydrolyzing] in Nitrosopumilus maritimus
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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guaAGMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (507 aa)    
Predicted Functional Partners:
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (476 aa)
 
  0.999
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates (533 aa)
   
 
  0.983
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (170 aa)
   
  0.973
Nmar_1008
D-alanine--D-alanine ligase; PFAM- peptidase M20; protein of unknown function DUF201; D-alanine--D-alanine ligase domain protein; RimK domain protein ATP-grasp; KEGG- amt-Amet_3744 D-alanine--D-alanine ligase domain protein (743 aa)
   
   
  0.968
Nmar_1530
TIGRFAM- non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM- Ham1 family protein; KEGG- mka-MK1594 xanthosine triphosphate pyrophosphatase; Belongs to the HAM1 NTPase family (188 aa)
 
 
  0.966
purL
Phosphoribosylformylglycinamidine synthase subunit PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (721 aa)
   
   
  0.946
Nmar_0068
PFAM- glutamine amidotransferase class-I; KEGG- pto-PTO1342 GMP synthase subunit A (180 aa)
 
   
0.924
Nmar_0518
annotation not available (82 aa)
     
        0.918
Nmar_1572
KEGG- tpe-Tpen_0751 hypothetical protein (183 aa)
              0.917
Nmar_1455
TIGRFAM- adenylosuccinate lyase; PFAM- fumarate lyase; KEGG- mja-MJ0929 adenylosuccinate lyase (453 aa)
 
   
  0.881
Your Current Organism:
Nitrosopumilus maritimus
NCBI taxonomy Id: 436308
Other names: N. maritimus SCM1, Nitrosopumilus maritimus, Nitrosopumilus maritimus SCM1, Nitrosopumilus maritimus str. SCM1, Nitrosopumilus maritimus strain SCM1, Seattle Aquarium strain SCM1
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