node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC109954824 | ivd | ENSMALP00000000560 | ENSMALP00000014448 | 4-hydroxyphenylpyruvate dioxygenase. | Isovaleryl-CoA dehydrogenase. | 0.516 |
LOC109954824 | mccc1 | ENSMALP00000000560 | ENSMALP00000028553 | 4-hydroxyphenylpyruvate dioxygenase. | Methylcrotonoyl-CoA carboxylase 1 (alpha). | 0.751 |
LOC109954824 | mccc2 | ENSMALP00000000560 | ENSMALP00000001869 | 4-hydroxyphenylpyruvate dioxygenase. | Methylcrotonoyl-CoA carboxylase 2 (beta). | 0.804 |
LOC109954824 | nelfcd | ENSMALP00000000560 | ENSMALP00000024806 | 4-hydroxyphenylpyruvate dioxygenase. | Negative elongation factor complex member C/D. | 0.751 |
LOC109954824 | pc | ENSMALP00000000560 | ENSMALP00000027872 | 4-hydroxyphenylpyruvate dioxygenase. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.668 |
LOC109954824 | pcca | ENSMALP00000000560 | ENSMALP00000014174 | 4-hydroxyphenylpyruvate dioxygenase. | Propionyl-CoA carboxylase subunit alpha. | 0.751 |
bckdha | hmgcl | ENSMALP00000013321 | ENSMALP00000015835 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 3-hydroxy-3-methylglutaryl-CoA lyase. | 0.619 |
bckdha | hmgcll1 | ENSMALP00000013321 | ENSMALP00000001241 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1. | 0.619 |
bckdha | ivd | ENSMALP00000013321 | ENSMALP00000014448 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Isovaleryl-CoA dehydrogenase. | 0.864 |
bckdha | mccc1 | ENSMALP00000013321 | ENSMALP00000028553 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Methylcrotonoyl-CoA carboxylase 1 (alpha). | 0.638 |
bckdha | mccc2 | ENSMALP00000013321 | ENSMALP00000001869 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Methylcrotonoyl-CoA carboxylase 2 (beta). | 0.822 |
bckdha | nelfcd | ENSMALP00000013321 | ENSMALP00000024806 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Negative elongation factor complex member C/D. | 0.633 |
bckdha | pc | ENSMALP00000013321 | ENSMALP00000027872 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.481 |
bckdha | pcca | ENSMALP00000013321 | ENSMALP00000014174 | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | Propionyl-CoA carboxylase subunit alpha. | 0.638 |
hlcs | mccc1 | ENSMALP00000020458 | ENSMALP00000028553 | Holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase). | Methylcrotonoyl-CoA carboxylase 1 (alpha). | 0.829 |
hlcs | mccc2 | ENSMALP00000020458 | ENSMALP00000001869 | Holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase). | Methylcrotonoyl-CoA carboxylase 2 (beta). | 0.823 |
hlcs | nelfcd | ENSMALP00000020458 | ENSMALP00000024806 | Holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase). | Negative elongation factor complex member C/D. | 0.802 |
hlcs | pc | ENSMALP00000020458 | ENSMALP00000027872 | Holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase). | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.986 |
hlcs | pcca | ENSMALP00000020458 | ENSMALP00000014174 | Holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase). | Propionyl-CoA carboxylase subunit alpha. | 0.829 |
hmgcl | bckdha | ENSMALP00000015835 | ENSMALP00000013321 | 3-hydroxy-3-methylglutaryl-CoA lyase. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.619 |