node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AZC_1598 | AZC_2207 | AZC_1598 | AZC_2207 | Para-aminobenzoate synthase; Component I. | Glutamine amidotransferase of anthranilate synthase. | 0.999 |
AZC_1598 | AZC_3375 | AZC_1598 | AZC_3375 | Para-aminobenzoate synthase; Component I. | Putative chorismate mutase. | 0.825 |
AZC_1598 | aroA | AZC_1598 | AZC_3931 | Para-aminobenzoate synthase; Component I. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.418 |
AZC_1598 | aroB | AZC_1598 | AZC_4489 | Para-aminobenzoate synthase; Component I. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.605 |
AZC_1598 | aroC | AZC_1598 | AZC_1749 | Para-aminobenzoate synthase; Component I. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.938 |
AZC_1598 | aroE | AZC_1598 | AZC_0003 | Para-aminobenzoate synthase; Component I. | Quinate shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.503 |
AZC_1598 | aroK | AZC_1598 | AZC_4488 | Para-aminobenzoate synthase; Component I. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.568 |
AZC_1598 | trpE | AZC_1598 | AZC_2208 | Para-aminobenzoate synthase; Component I. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.837 |
AZC_2207 | AZC_1598 | AZC_2207 | AZC_1598 | Glutamine amidotransferase of anthranilate synthase. | Para-aminobenzoate synthase; Component I. | 0.999 |
AZC_2207 | AZC_3375 | AZC_2207 | AZC_3375 | Glutamine amidotransferase of anthranilate synthase. | Putative chorismate mutase. | 0.918 |
AZC_2207 | AZC_4618 | AZC_2207 | AZC_4618 | Glutamine amidotransferase of anthranilate synthase. | Prephenate dehydrogenase precursor. | 0.475 |
AZC_2207 | aroA | AZC_2207 | AZC_3931 | Glutamine amidotransferase of anthranilate synthase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.584 |
AZC_2207 | aroB | AZC_2207 | AZC_4489 | Glutamine amidotransferase of anthranilate synthase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). | 0.770 |
AZC_2207 | aroC | AZC_2207 | AZC_1749 | Glutamine amidotransferase of anthranilate synthase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.977 |
AZC_2207 | aroE | AZC_2207 | AZC_0003 | Glutamine amidotransferase of anthranilate synthase. | Quinate shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.653 |
AZC_2207 | aroK | AZC_2207 | AZC_4488 | Glutamine amidotransferase of anthranilate synthase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.678 |
AZC_2207 | hisC | AZC_2207 | AZC_4619 | Glutamine amidotransferase of anthranilate synthase. | Histidinol-phosphate aminotransferase precursor; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.506 |
AZC_2207 | trpE | AZC_2207 | AZC_2208 | Glutamine amidotransferase of anthranilate synthase. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
AZC_3375 | AZC_1598 | AZC_3375 | AZC_1598 | Putative chorismate mutase. | Para-aminobenzoate synthase; Component I. | 0.825 |
AZC_3375 | AZC_2207 | AZC_3375 | AZC_2207 | Putative chorismate mutase. | Glutamine amidotransferase of anthranilate synthase. | 0.918 |