STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dalk_1193TIGRFAM: leucyl-tRNA synthetase; KEGG: dol:Dole_2438 leucyl-tRNA synthetase; IMG reference gene:2503006895; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family. (863 aa)    
Predicted Functional Partners:
Dalk_0026
Methionyl-tRNA synthetase; methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; IMG reference gene:2503005721; PFAM: Anticodon-binding domain; tRNA synthetases class I (M); Putative tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta [...]
 
0.999
Dalk_1770
TIGRFAM: isoleucyl-tRNA synthetase; KEGG: sfu:Sfum_0122 isoleucyl-tRNA synthetase; IMG reference gene:2503007481; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; Zinc finger found in FPG and IleRS; TIGRFAM: isoleucyl-tRNA synthetase.
 
0.994
Dalk_4293
TIGRFAM: glutamyl-tRNA synthetase; PFAM: glutamyl-tRNA synthetase class Ic; KEGG: dol:Dole_2533 glutamyl-tRNA synthetase; IMG reference gene:2503010041; PFAM: tRNA synthetases class I (E and Q), catalytic domain; TIGRFAM: glutamyl-tRNA synthetase, bacterial family.
 
 0.992
Dalk_1802
KEGG: dol:Dole_3039 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; IMG reference gene:2503007513; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial.
  
  
 0.991
Dalk_3446
Glutaminyl-tRNA synthetase; Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; IMG reference gene:2503009178; PFAM: tRNA synthetases class I (E and Q), catalytic domain; tRNA synthetases class I (E and Q), anti-codon binding domain; TIGRFAM: glutaminyl-tRNA synthetase.
  
 0.989
Dalk_4496
KEGG: dol:Dole_3215 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; IMG reference gene:2503010247; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase.
  
 0.989
Dalk_1784
TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; KEGG: dol:Dole_2847 lysyl-tRNA synthetase; IMG reference gene:2503007495; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial.
  
 0.986
Dalk_4284
Asparaginyl-tRNA synthetase; Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; IMG reference gene:2503010032; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase.
  
 0.984
Dalk_5106
Catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); IMG reference gene:2503010865; PFAM: Anticodon binding domain; Prolyl-tRNA synthetase, C-terminal; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: prolyl-tRNA synthetase, family I.
  
 0.981
Dalk_1183
KEGG: dol:Dole_2445 DNA topoisomerase I; TIGRFAM: DNA topoisomerase I; PFAM: TOPRIM domain protein; DNA topoisomerase type IA central domain protein; DNA topoisomerase type IA zn finger domain protein; SMART: DNA topoisomerase I ATP-binding; DNA topoisomerase I DNA-binding; Toprim sub domain protein; IMG reference gene:2503006885; PFAM: Toprim domain; Topoisomerase DNA binding C4 zinc finger; DNA topoisomerase; TIGRFAM: DNA topoisomerase I, bacterial.
   
 
 0.978
Your Current Organism:
Desulfatibacillum alkenivorans AK01
NCBI taxonomy Id: 439235
Other names: D. alkenivorans AK-01, Desulfatibacillum alkenivorans AK-01, Desulfatibacillum alkenivorans str. AK-01, Desulfatibacillum alkenivorans strain AK-01
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