STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dalk_3406ATP phosphoribosyltransferase; Long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; IMG reference gene:2503009138; PFAM: HisG, C-terminal domain; ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase, C-terminal domain; ATP phosphoribosyltransferase. (292 aa)    
Predicted Functional Partners:
Dalk_3405
PFAM: phosphoribosyl-AMP cyclohydrolase; KEGG: dol:Dole_1119 phosphoribosyl-AMP cyclohydrolase; IMG reference gene:2503009137; PFAM: Phosphoribosyl-AMP cyclohydrolase.
 
 
 0.998
Dalk_0826
PFAM: histidinol dehydrogenase; KEGG: sfu:Sfum_3299 histidinol dehydrogenase; IMG reference gene:2503006527; PFAM: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase.
 
 0.996
Dalk_3080
PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: lfe:LAF_0758 imidazoleglycerol-phosphate dehydratase; IMG reference gene:2503008809; PFAM: Imidazoleglycerol-phosphate dehydratase.
 
  
 0.979
Dalk_3078
TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: dol:Dole_2154 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; IMG reference gene:2503008807; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
  
 
 0.978
Dalk_2581
Imidazoleglycerol phosphate synthase, cyclase subunit; Catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; IMG reference gene:2503008302; PFAM: Histidine biosynthesis protein; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit.
 
 0.973
Dalk_2757
KEGG: dol:Dole_0669 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; IMG reference gene:2503008480; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase.
  
 0.973
Dalk_0635
PFAM: histidine biosynthesis protein; KEGG: pmt:PMT0100 imidazoleglycerol-phosphate synthase, cyclase subunit; IMG reference gene:2503006336; PFAM: Histidine biosynthesis protein; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit.
 
 0.961
Dalk_1314
Histidine biosynthesis protein; Catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamide and glutamine to imidazole-glycerolphosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; IMG reference gene:2503007018; PFAM: Histidine biosynthesis protein; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit.
 
 0.955
Dalk_0177
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: sfu:Sfum_2015 histidinol-phosphate aminotransferase; IMG reference gene:2503005872; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase.
 
  
 0.910
Dalk_1315
TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; PFAM: glutamine amidotransferase class-I; CobB/CobQ domain protein glutamine amidotransferase; KEGG: bba:Bd1691 imidazole glycerol phosphate synthase subunit HisH; IMG reference gene:2503007019; PFAM: Glutamine amidotransferase class-I; TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit.
 
  
 0.904
Your Current Organism:
Desulfatibacillum alkenivorans AK01
NCBI taxonomy Id: 439235
Other names: D. alkenivorans AK-01, Desulfatibacillum alkenivorans AK-01, Desulfatibacillum alkenivorans str. AK-01, Desulfatibacillum alkenivorans strain AK-01
Server load: medium (80%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.