STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dalk_5293KEGG: dol:Dole_0633 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; IMG reference gene:2503011053; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase. (333 aa)    
Predicted Functional Partners:
Dalk_3380
Phosphoserine aminotransferase; Catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; IMG reference gene:2503009111; PFAM: Aminotransferase class-V; TIGRFAM: phosphoserine aminotransferase.
     
 0.908
Dalk_3327
Pyridoxal phosphate biosynthetic protein PdxJ; Involved in the de novo synthesis of pyridoxine (Vitamin B6); IMG reference gene:2503009057; PFAM: Pyridoxal phosphate biosynthesis protein PdxJ; TIGRFAM: pyridoxine 5'-phosphate synthase.
 
  
 0.852
Dalk_4111
KEGG: dol:Dole_0095 DNA gyrase, B subunit; TIGRFAM: DNA gyrase, B subunit; PFAM: DNA gyrase subunit B domain protein; ATP-binding region ATPase domain protein; TOPRIM domain protein; DNA topoisomerase type IIA subunit B region 2 domain protein; SMART: DNA topoisomerase II; IMG reference gene:2503009857; PFAM: Toprim domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus; TIGRFAM: DNA gyrase, B subunit.
      0.822
Dalk_3122
TIGRFAM: dimethyladenosine transferase; PFAM: ribosomal RNA adenine methylase transferase; KEGG: dol:Dole_1636 dimethyladenosine transferase; IMG reference gene:2503008851; PFAM: Ribosomal RNA adenine dimethylase; TIGRFAM: dimethyladenosine transferase.
 
  
 0.808
Dalk_4397
KEGG: dol:Dole_2746 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; IMG reference gene:2503010145; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase.
    
 0.802
Dalk_5292
PFAM: protein of unknown function DUF980; KEGG: dol:Dole_0055 hypothetical protein; IMG reference gene:2503011052; PFAM: Phosphoenolpyruvate:glucose-phosphotransferase regulator.
       0.752
Dalk_3314
KEGG: dol:Dole_2077 3,4-dihydroxy-2-butanone 4-phosphate synthase; TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; PFAM: 34-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; IMG reference gene:2503009044; PFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase; TIGRFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase.
  
  
 0.545
Dalk_3456
KEGG: ypb:YPTS_0831 tartrate/fumarate subfamily Fe-S type hydro-lyase beta subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; IMG reference gene:2503009188; PFAM: Fumarase C-terminus; Fumarate hydratase (Fumerase); TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region; hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region.
  
    0.489
Dalk_1941
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; TonB box domain protein; KEGG: ppd:Ppro_2630 oxidoreductase FAD/NAD(P)-binding subunit; IMG reference gene:2503007658; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain.
    
  0.482
Dalk_4359
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: dol:Dole_0316 ferredoxin--NADP(+) reductase subunit alpha; IMG reference gene:2503010107; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain.
    
  0.482
Your Current Organism:
Desulfatibacillum alkenivorans AK01
NCBI taxonomy Id: 439235
Other names: D. alkenivorans AK-01, Desulfatibacillum alkenivorans AK-01, Desulfatibacillum alkenivorans str. AK-01, Desulfatibacillum alkenivorans strain AK-01
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.