node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mpop_3123 | ddl | Mpop_3123 | Mpop_3130 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.938 |
Mpop_3123 | mraY | Mpop_3123 | Mpop_5175 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.955 |
Mpop_3123 | murC | Mpop_3123 | Mpop_3125 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.977 |
Mpop_3123 | murD | Mpop_3123 | Mpop_5174 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.952 |
Mpop_3123 | murE | Mpop_3123 | Mpop_5177 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.835 |
Mpop_3123 | murF | Mpop_3123 | Mpop_5176 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.934 |
Mpop_3123 | murG | Mpop_3123 | Mpop_3124 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.981 |
Mpop_3123 | murI | Mpop_3123 | Mpop_3412 | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.488 |
ddl | Mpop_3123 | Mpop_3130 | Mpop_3123 | D-alanine--D-alanine ligase; Cell wall formation. | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | 0.938 |
ddl | mraY | Mpop_3130 | Mpop_5175 | D-alanine--D-alanine ligase; Cell wall formation. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.927 |
ddl | murC | Mpop_3130 | Mpop_3125 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.989 |
ddl | murD | Mpop_3130 | Mpop_5174 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.948 |
ddl | murE | Mpop_3130 | Mpop_5177 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.918 |
ddl | murF | Mpop_3130 | Mpop_5176 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.996 |
ddl | murG | Mpop_3130 | Mpop_3124 | D-alanine--D-alanine ligase; Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.941 |
glsA | murD | Mpop_2331 | Mpop_5174 | PFAM: Glutaminase, core; KEGG: mex:Mext_2375 glutaminase; Belongs to the glutaminase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.902 |
glsA | murI | Mpop_2331 | Mpop_3412 | PFAM: Glutaminase, core; KEGG: mex:Mext_2375 glutaminase; Belongs to the glutaminase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.924 |
glsA | purQ | Mpop_2331 | Mpop_0574 | PFAM: Glutaminase, core; KEGG: mex:Mext_2375 glutaminase; Belongs to the glutaminase family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.900 |
mraY | Mpop_3123 | Mpop_5175 | Mpop_3123 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | PFAM: cell cycle protein; KEGG: mex:Mext_2940 cell cycle protein; Belongs to the SEDS family. | 0.955 |
mraY | ddl | Mpop_5175 | Mpop_3130 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | D-alanine--D-alanine ligase; Cell wall formation. | 0.927 |