STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dpnIIType II site-specific deoxyribonuclease; Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1; Belongs to the type II restriction enzyme DpnII family. (283 aa)    
Predicted Functional Partners:
ACL_1084
DNA methylase, N6 adenine-specific.
 
   
 0.948
ACL_1083
DNA methylase; Belongs to the N(4)/N(6)-methyltransferase family.
 
     0.918
ACL_1081
Hypothetical protein.
       0.655
nfo
Endodeoxyribonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
     
 0.527
rnr
3'-5' exoribonuclease, RNase R/RNase II family; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
      
 0.463
ACL_1085
Serine recombinase, site-specific.
       0.453
ACL_1080
Hypothetical protein.
       0.432
Your Current Organism:
Acholeplasma laidlawii
NCBI taxonomy Id: 441768
Other names: A. laidlawii PG-8A, Acholeplasma laidlawii PG-8A, Acholeplasma laidlawii str. PG-8A, Acholeplasma laidlawii strain PG-8A
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.